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Protein- and growth-modulatory effects of carcinoma-associated fibroblasts on breast cancer cells: Role of interleukin-6

Carcinoma-associated fibroblasts (CAFs) secrete factors that increase the expression and/or activities of proteins in breast cancer cells and induce resistance to anti-estrogens, such as fulvestrant. A major factor is interleukin-6 (IL-6). This study demonstrated that, across estrogen receptor (ER)...

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Detalles Bibliográficos
Autores principales: Dittmer, Angela, Lange, Theresia, Leyh, Benjamin, Dittmer, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910226/
https://www.ncbi.nlm.nih.gov/pubmed/31789400
http://dx.doi.org/10.3892/ijo.2019.4918