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Cellular Interactome Dynamics during Paclitaxel Treatment

Cell-cycle inhibitors, including paclitaxel, are among the most widely used and effective cancer therapies. However, several challenges limit the success of paclitaxel, including drug resistance and toxic side effects. Paclitaxel is thought to act primarily by stabilizing microtubules, locking cells...

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Detalles Bibliográficos
Autores principales: Chavez, Juan D., Keller, Andrew, Zhou, Bo, Tian, Rong, Bruce, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910234/
https://www.ncbi.nlm.nih.gov/pubmed/31747606
http://dx.doi.org/10.1016/j.celrep.2019.10.063