Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing

CRISPR-Cas9 systems provide powerful tools for genome editing. However, optimal employment of this technology will require control of Cas9 activity so that the timing, tissue specificity, and accuracy of editing may be precisely modulated. Anti-CRISPR proteins, which are small, naturally occurring i...

Descripción completa

Detalles Bibliográficos
Autores principales: Garcia, Bianca, Lee, Jooyoung, Edraki, Alireza, Hidalgo-Reyes, Yurima, Erwood, Steven, Mir, Aamir, Trost, Chantel N., Seroussi, Uri, Stanley, Sabrina Y., Cohn, Ronald D., Claycomb, Julie M., Sontheimer, Erik J., Maxwell, Karen L., Davidson, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910239/
https://www.ncbi.nlm.nih.gov/pubmed/31722192
http://dx.doi.org/10.1016/j.celrep.2019.10.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910239/
https://www.ncbi.nlm.nih.gov/pubmed/31722192
http://dx.doi.org/10.1016/j.celrep.2019.10.017

Ejemplares similares