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Rho-associated kinase and zipper-interacting protein kinase, but not myosin light chain kinase, are involved in the regulation of myosin phosphorylation in serum-stimulated human arterial smooth muscle cells
Myosin regulatory light chain (LC(20)) phosphorylation plays an important role in vascular smooth muscle contraction and cell migration. Ca(2+)/calmodulin-dependent myosin light chain kinase (MLCK) phosphorylates LC(20) (its only known substrate) exclusively at S19. Rho-associated kinase (ROCK) and...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910671/ https://www.ncbi.nlm.nih.gov/pubmed/31834925 http://dx.doi.org/10.1371/journal.pone.0226406 |