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Do cancer stem cells exist? A pilot study combining a systematic review with the hierarchy-of-hypotheses approach

The phenomenon of cancer cell heterogeneity has been explained by different hypotheses, each entailing different therapy strategies. The most recent is the cancer stem cell model, which says that tumourigenicity and self-renewal are restricted to rare stem cell-like cancer cells. Since its conceptio...

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Detalles Bibliográficos
Autores principales: Bartram, Isabelle, Jeschke, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910685/
https://www.ncbi.nlm.nih.gov/pubmed/31834886
http://dx.doi.org/10.1371/journal.pone.0225898