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lncRNA GAS5/miR-452-5p Reduces Oxidative Stress and Pyroptosis of High-Glucose-Stimulated Renal Tubular Cells

BACKGROUND: Diabetic nephropathy (DN) is the leading cause of end-stage renal failure worldwide. lncRNAs are demonstrated to improve the DN by changing the expression of miRNAs. This study was aimed to investigate the effect of lncRNA GAS5/miR-452-5p on the inflammation, oxidative stress and pyropto...

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Detalles Bibliográficos
Autores principales: Xie, Cuisong, Wu, Weiling, Tang, Ainan, Luo, Ning, Tan, Yanfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910862/
https://www.ncbi.nlm.nih.gov/pubmed/31849505
http://dx.doi.org/10.2147/DMSO.S228654