Engineering protein assemblies with allosteric control via monomer fold-switching

The macromolecular machines of life use allosteric control to self-assemble, dissociate and change shape in response to signals. Despite enormous interest, the design of nanoscale allosteric assemblies has proven tremendously challenging. Here we present a proof of concept of allosteric assembly in...

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Detalles Bibliográficos
Autores principales: Campos, Luis A., Sharma, Rajendra, Alvira, Sara, Ruiz, Federico M., Ibarra-Molero, Beatriz, Sadqi, Mourad, Alfonso, Carlos, Rivas, Germán, Sanchez-Ruiz, Jose M., Romero Garrido, Antonio, Valpuesta, José M., Muñoz, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911049/
https://www.ncbi.nlm.nih.gov/pubmed/31836707
http://dx.doi.org/10.1038/s41467-019-13686-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911049/
https://www.ncbi.nlm.nih.gov/pubmed/31836707
http://dx.doi.org/10.1038/s41467-019-13686-1

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