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Engineering protein assemblies with allosteric control via monomer fold-switching
The macromolecular machines of life use allosteric control to self-assemble, dissociate and change shape in response to signals. Despite enormous interest, the design of nanoscale allosteric assemblies has proven tremendously challenging. Here we present a proof of concept of allosteric assembly in...
Autores principales: | Campos, Luis A., Sharma, Rajendra, Alvira, Sara, Ruiz, Federico M., Ibarra-Molero, Beatriz, Sadqi, Mourad, Alfonso, Carlos, Rivas, Germán, Sanchez-Ruiz, Jose M., Romero Garrido, Antonio, Valpuesta, José M., Muñoz, Victor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911049/ https://www.ncbi.nlm.nih.gov/pubmed/31836707 http://dx.doi.org/10.1038/s41467-019-13686-1 |
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