Predicting clinical decline and conversion to Alzheimer’s disease or dementia using novel Elecsys Aβ(1–42), pTau and tTau CSF immunoassays

We evaluated the performance of CSF biomarkers for predicting risk of clinical decline and conversion to dementia in non-demented patients with cognitive symptoms. CSF samples from patients in two multicentre longitudinal studies (ADNI, n = 619; BioFINDER, n = 431) were analysed. Aβ(1–42), tTau and...

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Detalles Bibliográficos
Autores principales: Blennow, Kaj, Shaw, Leslie M., Stomrud, Erik, Mattsson, Niklas, Toledo, Jon B., Buck, Katharina, Wahl, Simone, Eichenlaub, Udo, Lifke, Valeria, Simon, Maryline, Trojanowski, John Q., Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911086/
https://www.ncbi.nlm.nih.gov/pubmed/31836810
http://dx.doi.org/10.1038/s41598-019-54204-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911086/
https://www.ncbi.nlm.nih.gov/pubmed/31836810
http://dx.doi.org/10.1038/s41598-019-54204-z

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