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Evolutionary regain of lost gene circuit function

Evolutionary reversibility—the ability to regain a lost function—is an important problem both in evolutionary and synthetic biology, where repairing natural or synthetic systems broken by evolutionary processes may be valuable. Here, we use a synthetic positive-feedback (PF) gene circuit integrated...

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Detalles Bibliográficos
Autores principales: Kheir Gouda, Mirna, Manhart, Michael, Balázsi, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911209/
https://www.ncbi.nlm.nih.gov/pubmed/31754027
http://dx.doi.org/10.1073/pnas.1912257116