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Evolutionary regain of lost gene circuit function
Evolutionary reversibility—the ability to regain a lost function—is an important problem both in evolutionary and synthetic biology, where repairing natural or synthetic systems broken by evolutionary processes may be valuable. Here, we use a synthetic positive-feedback (PF) gene circuit integrated...
Autores principales: | Kheir Gouda, Mirna, Manhart, Michael, Balázsi, Gábor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911209/ https://www.ncbi.nlm.nih.gov/pubmed/31754027 http://dx.doi.org/10.1073/pnas.1912257116 |
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