Single-molecule imaging of HIV-1 envelope glycoprotein dynamics and Gag lattice association exposes determinants responsible for virus incorporation

The HIV-1 envelope glycoprotein (Env) is sparsely incorporated onto assembling virus particles on the host cell plasma membrane in order for the virus to balance infectivity and evade the immune response. Env becomes trapped in a nascent particle on encounter with the polymeric viral protein Gag, wh...

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Detalles Bibliográficos
Autores principales: Pezeshkian, Nairi, Groves, Nicholas S., van Engelenburg, Schuyler B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911212/
https://www.ncbi.nlm.nih.gov/pubmed/31757854
http://dx.doi.org/10.1073/pnas.1910008116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911212/
https://www.ncbi.nlm.nih.gov/pubmed/31757854
http://dx.doi.org/10.1073/pnas.1910008116

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