A structural basis for antibody-mediated neutralization of Nipah virus reveals a site of vulnerability at the fusion glycoprotein apex

Nipah virus (NiV) is a highly pathogenic paramyxovirus that causes frequent outbreaks of severe neurologic and respiratory disease in humans with high case fatality rates. The 2 glycoproteins displayed on the surface of the virus, NiV-G and NiV-F, mediate host-cell attachment and membrane fusion, re...

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Detalles Bibliográficos
Autores principales: Avanzato, Victoria A., Oguntuyo, Kasopefoluwa Y., Escalera-Zamudio, Marina, Gutierrez, Bernardo, Golden, Michael, Kosakovsky Pond, Sergei L., Pryce, Rhys, Walter, Thomas S., Seow, Jeffrey, Doores, Katie J., Pybus, Oliver G., Munster, Vincent J., Lee, Benhur, Bowden, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911215/
https://www.ncbi.nlm.nih.gov/pubmed/31767754
http://dx.doi.org/10.1073/pnas.1912503116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911215/
https://www.ncbi.nlm.nih.gov/pubmed/31767754
http://dx.doi.org/10.1073/pnas.1912503116

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