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A structural basis for antibody-mediated neutralization of Nipah virus reveals a site of vulnerability at the fusion glycoprotein apex

Nipah virus (NiV) is a highly pathogenic paramyxovirus that causes frequent outbreaks of severe neurologic and respiratory disease in humans with high case fatality rates. The 2 glycoproteins displayed on the surface of the virus, NiV-G and NiV-F, mediate host-cell attachment and membrane fusion, re...

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Detalles Bibliográficos
Autores principales:	Avanzato, Victoria A., Oguntuyo, Kasopefoluwa Y., Escalera-Zamudio, Marina, Gutierrez, Bernardo, Golden, Michael, Kosakovsky Pond, Sergei L., Pryce, Rhys, Walter, Thomas S., Seow, Jeffrey, Doores, Katie J., Pybus, Oliver G., Munster, Vincent J., Lee, Benhur, Bowden, Thomas A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2019
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911215/ https://www.ncbi.nlm.nih.gov/pubmed/31767754 http://dx.doi.org/10.1073/pnas.1912503116

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