Structure and Drug Resistance of the Plasmodium falciparum Transporter PfCRT

The emergence and spread of drug-resistant Plasmodium falciparum impedes global efforts to control and eliminate malaria. For decades, treatment relied on chloroquine (CQ), a safe and affordable 4-aminoquinoline that was highly effective against intra-erythrocytic asexual blood-stage parasites, unti...

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Detalles Bibliográficos
Autores principales: Kim, Jonathan, Tan, Yong Zi, Wicht, Kathryn J., Erramilli, Satchal K., Dhingra, Satish K., Okombo, John, Vendome, Jeremie, Hagenah, Laura M., Giacometti, Sabrina I., Warren, Audrey L., Nosol, Kamil, Roepe, Paul D., Potter, Clinton S., Carragher, Bridget, Kossiakoff, Anthony A., Quick, Matthias, Fidock, David A., Mancia, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911266/
https://www.ncbi.nlm.nih.gov/pubmed/31776516
http://dx.doi.org/10.1038/s41586-019-1795-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911266/
https://www.ncbi.nlm.nih.gov/pubmed/31776516
http://dx.doi.org/10.1038/s41586-019-1795-x

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