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Protein tyrosine phosphatase PTPN1 modulates cell growth and associates with poor outcome in human neuroblastoma

BACKGROUND: Protein tyrosine phosphatases (PTPs) regulate neuronal differentiation and survival, but their expression patterns and functions in human neuroblastoma (NB) are scarcely known. Here, we have investigated the function and expression of the non-receptor PTPN1 on human NB cell lines and hum...

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Detalles Bibliográficos
Autores principales: Nunes-Xavier, Caroline E., Aurtenetxe, Olaia, Zaldumbide, Laura, López-Almaraz, Ricardo, Erramuzpe, Asier, Cortés, Jesús M., López, José I., Pulido, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911276/
https://www.ncbi.nlm.nih.gov/pubmed/31837707
http://dx.doi.org/10.1186/s13000-019-0919-9