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Blocking AMPK/ULK1-dependent autophagy promoted apoptosis and suppressed colon cancer growth

BACKGROUND: Autophagy is an evolutionarily conserved process through which cells degrade and recycle cytoplasm. The relation among autophagy, apoptosis and tumor is highly controversial until now and the molecular mechanism is poorly understood. METHODS: Cell viability and apoptosis were detected by...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Long, Shuaiyu, Wang, Huanan, Liu, Nannan, Zhang, Chuchu, Zhang, Lingling, Zhang, Yingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911288/
https://www.ncbi.nlm.nih.gov/pubmed/31871431
http://dx.doi.org/10.1186/s12935-019-1054-0