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Blocking AMPK/ULK1-dependent autophagy promoted apoptosis and suppressed colon cancer growth
BACKGROUND: Autophagy is an evolutionarily conserved process through which cells degrade and recycle cytoplasm. The relation among autophagy, apoptosis and tumor is highly controversial until now and the molecular mechanism is poorly understood. METHODS: Cell viability and apoptosis were detected by...
Autores principales: | Liu, Jing, Long, Shuaiyu, Wang, Huanan, Liu, Nannan, Zhang, Chuchu, Zhang, Lingling, Zhang, Yingjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911288/ https://www.ncbi.nlm.nih.gov/pubmed/31871431 http://dx.doi.org/10.1186/s12935-019-1054-0 |
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