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TIMP-2 secreted by monocyte-like cells is a potent suppressor of invadopodia formation in pancreatic cancer cells
BACKGROUND: Monocytes are a major component of the tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDAC). However, the complex interactions between tumor cells and monocytes and their role in tumor invasion have not been fully established. METHODS: To specifically test the impact o...
Autores principales: | Benzing, Christian, Lam, Hoyin, Tsang, Chi Man, Rimmer, Alexander, Arroyo-Berdugo, Yoana, Calle, Yolanda, Wells, Claire M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911299/ https://www.ncbi.nlm.nih.gov/pubmed/31836008 http://dx.doi.org/10.1186/s12885-019-6429-z |
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