Preparation of a Novel One-Armed Anti-c-Met Antibody with Antitumor Activity Against Hepatocellular Carcinoma

INTRODUCTION: Antibody-based c-mesenchymal–epithelial transition factor (c-Met) inhibition is a promising strategy for hepatocellular carcinoma (HCC) treatment, but the intrinsic agonistic activity of the anti-c-Met antibody limits its application in drug development. Constructing a monovalent one-a...

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Detalles Bibliográficos
Autores principales: Yin, Yanxin, Guo, Jia, Teng, Fei, Yu, Lihua, Jiang, Yun, Xie, Kun, Jiang, Ming, Fang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911325/
https://www.ncbi.nlm.nih.gov/pubmed/31849449
http://dx.doi.org/10.2147/DDDT.S224491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911325/
https://www.ncbi.nlm.nih.gov/pubmed/31849449
http://dx.doi.org/10.2147/DDDT.S224491

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