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Pharmacological Evaluation of Aldehydic-Pyrrolidinedione Against HCT-116, MDA-MB231, NIH/3T3, MCF-7 Cancer Cell Lines, Antioxidant and Enzyme Inhibition Studies

PURPOSE: The current work was designed to synthesize a bioactive derivative of succinimide and evaluate it for anti-Alzheimer, anticancer and anti-diabetic potentials. METHODS: The compound was synthesized by Michael addition of butyraldehyde with N-phenylmaleimide. The synthesized compound was scre...

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Detalles Bibliográficos
Autores principales: Ahmad, Ashfaq, Ullah, Farhat, Sadiq, Abdul, Ayaz, Muhammad, Rahim, Haroon, Rashid, Umer, Ahmad, Sajjad, Jan, Muhammad Saeed, Ullah, Riaz, Shahat, Abdelaaty A, Mahmood, Hafiz Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911349/
https://www.ncbi.nlm.nih.gov/pubmed/31849450
http://dx.doi.org/10.2147/DDDT.S226080