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Catalpol Enhances Neurogenesis And Inhibits Apoptosis Of New Neurons Via BDNF, But Not The BDNF/Trkb Pathway

BACKGROUND: The role of catalpol in brain neurogenesis and newborn neuron survival has not been previously determined in permanent middle cerebral artery occlusion (pMCAO). METHODS: Fifty-four rats were divided into 6 groups: pMCAO (model, n=9); sham operation (NS, n=9); catalpol treatment (5 mg/kg...

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Detalles Bibliográficos
Autores principales: Zhu, Hui-Feng, Shao, Yali, Qin, Lei, Wang, Jing-Huan, Feng, Shan, Jiang, Yun-Bin, Wan, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911350/
https://www.ncbi.nlm.nih.gov/pubmed/31849446
http://dx.doi.org/10.2147/DDDT.S223322