Small Cell Lung Cancer Derived from Adenocarcinoma with Mutant Epidermal Growth Factor Receptor Provides a Signature of Transcriptional Alteration in Tumor Cells

Small cell lung cancer (SCLC) transformation of epidermal growth factor receptor (EGFR) mutant adenocarcinoma (ADC) during EGFR tyrosine kinase inhibitor (TKI) treatment is an example of a rare subset of acquired drug resistance. We herein report the case of a 75-year-old man treated with afatinib w...

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Detalles Bibliográficos
Autores principales: Tenjin, Yuki, Nakamura, Kazuyoshi, Ishizuka, Shiho, Saruwatari, Koichi, Sato, Ryo, Tomita, Yusuke, Saeki, Sho, Ichiyasu, Hidenori, Fujii, Kazuhiko, Ito, Takaaki, Sakagami, Takuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911746/
https://www.ncbi.nlm.nih.gov/pubmed/31292388
http://dx.doi.org/10.2169/internalmedicine.2988-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911746/
https://www.ncbi.nlm.nih.gov/pubmed/31292388
http://dx.doi.org/10.2169/internalmedicine.2988-19

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