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Major bleeding events in octagenarians associated with drug interactions between dabigatran and P-gp inhibitors

BACKGROUND: The direct oral anticoagulant dabigatran does not require any routine therapeutic drug monitoring. Yet, concerns about possible drug interactions susceptible to increase its inherent bleeding risk, especially in very elderly patients, have been raised recently. The aim of our study was t...

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Detalles Bibliográficos
Autores principales: Bernier, Marjorie, Lancrerot, Sarah-Line, Rocher, Fanny, Van-Obberghen, Elise K, Olivier, Pierre, Lavrut, Thibaud, Parassol-Girard, Nadège, Drici, Milou-Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911799/
https://www.ncbi.nlm.nih.gov/pubmed/31853245
http://dx.doi.org/10.11909/j.issn.1671-5411.2019.11.002