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The Effect of Glutamatergic Modulators on Extracellular Glutamate: How Does this Information Contribute to the Discovery of Novel Antidepressants?
BACKGROUND: In the search for new antidepressants, clinical researchers have been using drugs that simultaneously modulate multiple targets. During preclinical and clinical trials, the glutamatergic modulators riluzole and ketamine have received particular attention. Glutamatergic agents have a modu...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911922/ https://www.ncbi.nlm.nih.gov/pubmed/31871505 http://dx.doi.org/10.1016/j.curtheres.2019.100566 |