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20(R)-Ginsenoside Rg3 Influences Cancer Stem Cell Properties and the Epithelial-Mesenchymal Transition in Colorectal Cancer via the SNAIL Signaling Axis

BACKGROUND: Cancer stem cells (CSCs) have been proposed as central drivers of cancer relapse in many cancers. In the present study, we investigated the inhibitory effect of 20(R)-Ginsenoside Rg3 (Rg3R), a major active component of ginseng saponin, on CSC-like cells and the Epithelial-Mesenchymal Tra...

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Detalles Bibliográficos
Autores principales: Phi, Lan Thi Hanh, Wijaya, Yoseph Toni, Sari, Ita Novita, Kim, Kwang Seock, Yang, Ying-Gui, Lee, Min-Woo, Kwon, Hyog Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912006/
https://www.ncbi.nlm.nih.gov/pubmed/31849492
http://dx.doi.org/10.2147/OTT.S219063