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Hypoxia‐induced HIF‐1α and ZEB1 are critical for the malignant transformation of ameloblastoma via TGF‐β‐dependent EMT

Ameloblastic carcinoma (AC) is defined as a rare primary epithelial odontogenic malignant neoplasm and the malignant counterpart of benign epithelial odontogenic tumor of ameloblastoma (AB) by the WHO classification. AC develops pulmonary metastasis in about one third of the patients and reveals a p...

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Detalles Bibliográficos
Autores principales: Yoshimoto, Shohei, Tanaka, Fumie, Morita, Hiromitsu, Hiraki, Akimitsu, Hashimoto, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912026/
https://www.ncbi.nlm.nih.gov/pubmed/31674718
http://dx.doi.org/10.1002/cam4.2667