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Targeted RNA‐sequencing assays: a step forward compared to FISH and IHC techniques?

INTRODUCTION: ALK and ROS1 rearrangements are molecular targets of several tyrosine kinase inhibitors. RNA‐sequencing approaches are regarded as the new standard for fusion gene detection, representing an alternative to standard immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH...

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Detalles Bibliográficos
Autores principales: Tachon, Gaëlle, Cortes, Ulrich, Richard, Sophie, Martin, Sébastien, Milin, Serge, Evrard, Camille, Lamour, Corinne, Karayan‐Tapon, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912030/
https://www.ncbi.nlm.nih.gov/pubmed/31651105
http://dx.doi.org/10.1002/cam4.2599