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PGC‐1α inhibits polyamine metabolism in Cyclin E1‐driven ovarian cancer

AIM: Cyclin E1‐driven ovarian cancer (OvCa) is characterized with metabolic shift. In this study, we aim to pinpoint the metabolic pathway altered and assess its therapeutic potential. METHODS: In silico reproduction of TCGA ovarian cancer dataset and functional annotation using GSEA was performed....

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Detalles Bibliográficos
Autores principales: Guo, Ting, Li, Bin, Gu, Chao, Chen, Xiuying, Han, Mengxin, Liu, Xiaocheng, Xu, Congjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912055/
https://www.ncbi.nlm.nih.gov/pubmed/31657115
http://dx.doi.org/10.1002/cam4.2637