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PGC‐1α inhibits polyamine metabolism in Cyclin E1‐driven ovarian cancer
AIM: Cyclin E1‐driven ovarian cancer (OvCa) is characterized with metabolic shift. In this study, we aim to pinpoint the metabolic pathway altered and assess its therapeutic potential. METHODS: In silico reproduction of TCGA ovarian cancer dataset and functional annotation using GSEA was performed....
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912055/ https://www.ncbi.nlm.nih.gov/pubmed/31657115 http://dx.doi.org/10.1002/cam4.2637 |