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Differential Modulation of Innate Immune Responses in Human Primary Cells by Influenza A Viruses Carrying Human or Avian Nonstructural Protein 1

The influenza A virus (IAV) nonstructural protein 1 (NS1) contributes to disease pathogenesis through the inhibition of host innate immune responses. Dendritic cells (DCs) release interferons (IFNs) and proinflammatory cytokines and promote adaptive immunity upon viral infection. In order to charact...

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Detalles Bibliográficos
Autores principales: Monteagudo, Paula L., Muñoz-Moreno, Raquel, Fribourg, Miguel, Potla, Uma, Mena, Ignacio, Marjanovic, Nada, Hartmann, Boris M., Sealfon, Stuart C., García-Sastre, Adolfo, Ramos, Irene, Fernández-Sesma, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912104/
https://www.ncbi.nlm.nih.gov/pubmed/31597767
http://dx.doi.org/10.1128/JVI.00999-19