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Lumen Expansion Facilitates Epiblast-Primitive Endoderm Fate Specification during Mouse Blastocyst Formation

Epithelial tissues typically form lumina. In mammalian blastocysts, in which the first embryonic lumen forms, many studies have investigated how the cell lineages are specified through genetics and signaling, whereas potential roles of the fluid lumen have yet to be investigated. We discover that in...

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Detalles Bibliográficos
Autores principales: Ryan, Allyson Quinn, Chan, Chii Jou, Graner, François, Hiiragi, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912163/
https://www.ncbi.nlm.nih.gov/pubmed/31735667
http://dx.doi.org/10.1016/j.devcel.2019.10.011