Piperlongumine Induces Cell Cycle Arrest via Reactive Oxygen Species Accumulation and IKKβ Suppression in Human Breast Cancer Cells

Piperlongumine (PL), a natural product derived from long pepper (Piper longum L.), is known to exhibit anticancer effects. However, the effect of PL on cell cycle-regulatory proteins in estrogen receptor (ER)-positive breast cancer cells is unclear. Therefore, we investigated whether PL can modulate...

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Detalles Bibliográficos
Autores principales: Jeong, Chang Hee, Ryu, Haram, Kim, Do Hyun, Cheng, Wei Nee, Yoon, Jee Eun, Kang, Sukyung, Han, Sung Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912225/
https://www.ncbi.nlm.nih.gov/pubmed/31739520
http://dx.doi.org/10.3390/antiox8110553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912225/
https://www.ncbi.nlm.nih.gov/pubmed/31739520
http://dx.doi.org/10.3390/antiox8110553

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