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Licochalcone A-Induced Apoptosis Through the Activation of p38MAPK Pathway Mediated Mitochondrial Pathways of Apoptosis in Human Osteosarcoma Cells In Vitro and In Vivo

Background: Licochalcone A (LicA) is isolated from the roots of Glycyrrhiza glabra and possesses antitumor and anti-invasive activities against several tumor cells. However, the antitumor effects of LicA on human osteosarcoma cells have yet to be demonstrated either in vitro or in vivo. Methods: Cel...

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Detalles Bibliográficos
Autores principales: Lin, Renn-Chia, Yang, Shun-Fa, Chiou, Hui-Ling, Hsieh, Shu-Ching, Wen, Shiua-Hua, Lu, Ko-Hsiu, Hsieh, Yi-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912226/
https://www.ncbi.nlm.nih.gov/pubmed/31739642
http://dx.doi.org/10.3390/cells8111441