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Identification of Novel Adenylyl Cyclase 5 (AC5) Signaling Networks in D(1) and D(2) Medium Spiny Neurons using Bimolecular Fluorescence Complementation Screening

Adenylyl cyclase type 5 (AC5), as the principal isoform expressed in striatal medium spiny neurons (MSNs), is essential for the integration of both stimulatory and inhibitory midbrain signals that initiate from dopaminergic G protein-coupled receptor (GPCR) activation. The spatial and temporal contr...

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Detalles Bibliográficos
Autores principales: Doyle, Trevor B., Muntean, Brian S., Ejendal, Karin F., Hayes, Michael P., Soto-Velasquez, Monica, Martemyanov, Kirill A., Dessauer, Carmen W., Hu, Chang-Deng, Watts, Val J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912275/
https://www.ncbi.nlm.nih.gov/pubmed/31752385
http://dx.doi.org/10.3390/cells8111468