Dyskerin Mutations Present in Dyskeratosis Congenita Patients Increase Oxidative Stress and DNA Damage Signalling in Dictyostelium Discoideum

Dyskerin is a protein involved in the formation of small nucleolar and small Cajal body ribonucleoproteins. These complexes participate in RNA pseudouridylation and are also components of the telomerase complex required for telomere elongation. Dyskerin mutations cause a rare disease, X-linked dyske...

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Detalles Bibliográficos
Autores principales: Rodriguez-Centeno, Javier, Perona, Rosario, Sastre, Leandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912284/
https://www.ncbi.nlm.nih.gov/pubmed/31717312
http://dx.doi.org/10.3390/cells8111406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912284/
https://www.ncbi.nlm.nih.gov/pubmed/31717312
http://dx.doi.org/10.3390/cells8111406

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