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Therapeutic Targeting of Cancer Stem Cells in Human Glioblastoma by Manipulating the Renin-Angiotensin System

Patients with glioblastoma (GB), a highly aggressive brain tumor, have a median survival of 14.6 months following neurosurgical resection and adjuvant chemoradiotherapy. Quiescent GB cancer stem cells (CSCs) invariably cause local recurrence. These GB CSCs can be identified by embryonic stem cell ma...

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Detalles Bibliográficos
Autores principales: Tan, David C. H., Roth, Imogen M., Wickremesekera, Agadha C., Davis, Paul F., Kaye, Andrew H., Mantamadiotis, Theo, Stylli, Stanley S., Tan, Swee T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912312/
https://www.ncbi.nlm.nih.gov/pubmed/31683669
http://dx.doi.org/10.3390/cells8111364