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A Role for H(2)O(2) and TRPM2 in the Induction of Cell Death: Studies in KGN Cells

Recent studies showed that KGN cells, derived from a human granulosa cell tumor (GCT), express NADPH oxidase 4 (NOX4), an important source of H(2)O(2). Transient receptor potential melastatin 2 (TRPM2) channel is a Ca(2+) permeable cation channel that can be activated by H(2)O(2) and plays an import...

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Detalles Bibliográficos
Autores principales: Hack, Carsten Theo, Buck, Theresa, Bagnjuk, Konstantin, Eubler, Katja, Kunz, Lars, Mayr, Doris, Mayerhofer, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912327/
https://www.ncbi.nlm.nih.gov/pubmed/31671815
http://dx.doi.org/10.3390/antiox8110518