TRPC6-Mediated ERK1/2 Activation Increases Dentate Granule Cell Resistance to Status Epilepticus via Regulating Lon Protease-1 Expression and Mitochondrial Dynamics

Transient receptor potential canonical channel-6 (TRPC6) is one of the Ca(2+)-permeable non-selective cation channels. TRPC6 is mainly expressed in dentate granule cell (DGC), which is one of the most resistant neuronal populations to various harmful stresses. Although TRPC6 knockdown evokes the mas...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Eun, Park, Hana, Choi, Seo-Hyeon, Kong, Min-Jeong, Kang, Tae-Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912337/
https://www.ncbi.nlm.nih.gov/pubmed/31683954
http://dx.doi.org/10.3390/cells8111376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912337/
https://www.ncbi.nlm.nih.gov/pubmed/31683954
http://dx.doi.org/10.3390/cells8111376

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