Recent Advances in EPAC-Targeted Therapies: A Biophysical Perspective

The universal second messenger cAMP regulates diverse intracellular processes by interacting with ubiquitously expressed proteins, such as Protein Kinase A (PKA) and the Exchange Protein directly Activated by cAMP (EPAC). EPAC is implicated in multiple pathologies, thus several EPAC-specific inhibit...

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Detalles Bibliográficos
Autores principales: Ahmed, Alveena, Boulton, Stephen, Shao, Hongzhao, Akimoto, Madoka, Natarajan, Amarnath, Cheng, Xiaodong, Melacini, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912387/
https://www.ncbi.nlm.nih.gov/pubmed/31752286
http://dx.doi.org/10.3390/cells8111462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912387/
https://www.ncbi.nlm.nih.gov/pubmed/31752286
http://dx.doi.org/10.3390/cells8111462

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