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The Role of Inflammasome-Dependent and Inflammasome-Independent NLRP3 in the Kidney

Cytoplasmic nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) forms an inflammasome with apoptosis-associated speck-like protein containing a CARD (ASC) and pro-caspase-1, which is followed by the cleavage of pro-caspase-1 to active caspase-1 and ultimately the activation of...

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Detalles Bibliográficos
Autores principales: Kim, Yang Gyun, Kim, Su-Mi, Kim, Ki-Pyo, Lee, Sang-Ho, Moon, Ju-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912448/
https://www.ncbi.nlm.nih.gov/pubmed/31694192
http://dx.doi.org/10.3390/cells8111389