Alternative Splicing of RAD6B and Not RAD6A Is Selectively Increased in Melanoma: Identification and Functional Characterization

Rad6B, a principal component of the translesion synthesis pathway, and activator of canonical Wnt signaling, plays an essential role in cutaneous melanoma development and progression. As Rad6 is encoded by two genes, namely, UBE2A (RAD6A) and UBE2B (RAD6B), in humans, we compared their expressions i...

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Detalles Bibliográficos
Autores principales: Gajan, Ambikai, Martin, Carly E., Kim, Seongho, Joshi, Milap, Michelhaugh, Sharon K., Sloma, Ido, Mittal, Sandeep, Firestine, Steven, Shekhar, Malathy P. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912459/
https://www.ncbi.nlm.nih.gov/pubmed/31683936
http://dx.doi.org/10.3390/cells8111375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912459/
https://www.ncbi.nlm.nih.gov/pubmed/31683936
http://dx.doi.org/10.3390/cells8111375

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