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Alternative Splicing of RAD6B and Not RAD6A Is Selectively Increased in Melanoma: Identification and Functional Characterization
Rad6B, a principal component of the translesion synthesis pathway, and activator of canonical Wnt signaling, plays an essential role in cutaneous melanoma development and progression. As Rad6 is encoded by two genes, namely, UBE2A (RAD6A) and UBE2B (RAD6B), in humans, we compared their expressions i...
Autores principales: | Gajan, Ambikai, Martin, Carly E., Kim, Seongho, Joshi, Milap, Michelhaugh, Sharon K., Sloma, Ido, Mittal, Sandeep, Firestine, Steven, Shekhar, Malathy P. V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912459/ https://www.ncbi.nlm.nih.gov/pubmed/31683936 http://dx.doi.org/10.3390/cells8111375 |
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