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Patient-Derived Head and Neck Cancer Organoids Recapitulate EGFR Expression Levels of Respective Tissues and Are Responsive to EGFR-Targeted Photodynamic Therapy

Patients diagnosed with head and neck squamous cell carcinoma (HNSCC) are currently treated with surgery and/or radio- and chemotherapy. Despite these therapeutic interventions, 40% of patients relapse, urging the need for more effective therapies. In photodynamic therapy (PDT), a light-activated ph...

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Detalles Bibliográficos
Autores principales: Driehuis, Else, Spelier, Sacha, Beltrán Hernández, Irati, de Bree, Remco, M. Willems, Stefan, Clevers, Hans, Oliveira, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912517/
https://www.ncbi.nlm.nih.gov/pubmed/31694307
http://dx.doi.org/10.3390/jcm8111880