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Cdc42 Couples T Cell Receptor Endocytosis to GRAF1-Mediated Tubular Invaginations of the Plasma Membrane

T cell activation is immediately followed by internalization of the T cell receptor (TCR). TCR endocytosis is required for T cell activation, but the mechanisms supporting removal of TCR from the cell surface remain incompletely understood. Here we report that TCR endocytosis is linked to the clathr...

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Detalles Bibliográficos
Autores principales: Rossatti, Pascal, Ziegler, Luca, Schregle, Richard, Betzler, Verena M., Ecker, Manuela, Rossy, Jérémie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912536/
https://www.ncbi.nlm.nih.gov/pubmed/31690048
http://dx.doi.org/10.3390/cells8111388