Cargando…
Cdc42 Couples T Cell Receptor Endocytosis to GRAF1-Mediated Tubular Invaginations of the Plasma Membrane
T cell activation is immediately followed by internalization of the T cell receptor (TCR). TCR endocytosis is required for T cell activation, but the mechanisms supporting removal of TCR from the cell surface remain incompletely understood. Here we report that TCR endocytosis is linked to the clathr...
Autores principales: | Rossatti, Pascal, Ziegler, Luca, Schregle, Richard, Betzler, Verena M., Ecker, Manuela, Rossy, Jérémie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912536/ https://www.ncbi.nlm.nih.gov/pubmed/31690048 http://dx.doi.org/10.3390/cells8111388 |
Ejemplares similares
-
SNX9-induced membrane tubulation regulates CD28 cluster stability and signalling
por: Ecker, Manuela, et al.
Publicado: (2022) -
Membrane Heterogeneity Controls Cellular Endocytic Trafficking
por: Redpath, Gregory M. I., et al.
Publicado: (2020) -
Endocytic membrane turnover at the leading edge is driven by a transient interaction between Cdc42 and GRAF1
por: Francis, Monika K., et al.
Publicado: (2015) -
Cdc42 activation couples fluid shear stress to apical endocytosis in proximal tubule cells
por: Bhattacharyya, Sohinee, et al.
Publicado: (2017) -
CEMIP, acting as a scaffold protein for bridging GRAF1 and MIB1, promotes colorectal cancer metastasis via activating CDC42/MAPK pathway
por: Xu, Guojie, et al.
Publicado: (2023)