A Matricryptic Conformation of the Integrin-Binding Domain of Fibronectin Regulates Platelet-Derived Growth Factor-Induced Intracellular Calcium Release

Platelet-derived growth factor (PDGF) signaling is dysregulated in a wide variety of diseases, making PDGF an attractive therapeutic target. However, PDGF also affects numerous signaling cascades essential for tissue homeostasis, limiting the development of PDGF-based therapies that lack adverse sid...

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Detalles Bibliográficos
Autores principales: Farrar, Christopher S., Rouin, Geoffrey T., Miller, Benjamin L., Raeman, Carol H., Mooney, Nancie A., Hocking, Denise C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912537/
https://www.ncbi.nlm.nih.gov/pubmed/31671632
http://dx.doi.org/10.3390/cells8111351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912537/
https://www.ncbi.nlm.nih.gov/pubmed/31671632
http://dx.doi.org/10.3390/cells8111351

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