Reductions of Circulating Nitric Oxide are Followed by Hypertension during Pregnancy and Increased Activity of Matrix Metalloproteinases-2 and -9 in Rats

Hypertensive pregnancy has been associated with reduced nitric oxide (NO), bioavailability, and increased activity of matrix metalloproteinases (MMPs). However, it is unclear if MMPs activation is regulated by NO during pregnancy. To this end, we examined activity of MMP-2 and MMP-9 in plasma, place...

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Detalles Bibliográficos
Autores principales: Nascimento, Regina A., Possomato-Vieira, Jose S., Bonacio, Giselle F., Rizzi, Elen, Dias-Junior, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912623/
https://www.ncbi.nlm.nih.gov/pubmed/31703340
http://dx.doi.org/10.3390/cells8111402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912623/
https://www.ncbi.nlm.nih.gov/pubmed/31703340
http://dx.doi.org/10.3390/cells8111402

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