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Reductions of Circulating Nitric Oxide are Followed by Hypertension during Pregnancy and Increased Activity of Matrix Metalloproteinases-2 and -9 in Rats
Hypertensive pregnancy has been associated with reduced nitric oxide (NO), bioavailability, and increased activity of matrix metalloproteinases (MMPs). However, it is unclear if MMPs activation is regulated by NO during pregnancy. To this end, we examined activity of MMP-2 and MMP-9 in plasma, place...
Autores principales: | Nascimento, Regina A., Possomato-Vieira, Jose S., Bonacio, Giselle F., Rizzi, Elen, Dias-Junior, Carlos A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912623/ https://www.ncbi.nlm.nih.gov/pubmed/31703340 http://dx.doi.org/10.3390/cells8111402 |
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