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Stem-Like Cancer Cells in a Dynamic 3D Culture System: A Model to Study Metastatic Cell Adhesion and Anti-Cancer Drugs

Metastatic spread is mainly sustained by cancer stem cells (CSC), a subpopulation of cancer cells that displays stemness features. CSC are thought to be derived from cancer cells that undergo epithelial to mesenchymal transition (EMT), thus acquiring resistance to anoikis and anti-cancer drugs. Afte...

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Detalles Bibliográficos
Autores principales: Paolillo, Mayra, Colombo, Raffaella, Serra, Massimo, Belvisi, Laura, Papetti, Adele, Ciusani, Emilio, Comincini, Sergio, Schinelli, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912649/
https://www.ncbi.nlm.nih.gov/pubmed/31766310
http://dx.doi.org/10.3390/cells8111434